A high-sensitivity C-reactive protein in assessing severity of asthma: A case control study

Original Article

Author Details : T.V. Uday Krishna, V Venkateswara Rao*, Syed Umer Ahmed, B Vishwanath

Volume : 6, Issue : 2, Year : 2021

Article Page : 86-89


Suggest article by email


Introduction: Asthma is often believed to be a disorder localized to the lungs, current evidence indicates that it may represent a component of systemic airway disease involving the entire respiratory tract. Despite significant improvements in the diagnosis and management of asthma over the past decade, as well as the availability of comprehensive and widely-accepted national and international clinical practice guidelines for the disease.
Materials and Methods: This is prospective and descriptive study patients were derived among patients with asthma presented for follow -up examination in outpatient Department of pulmonary Medicine of Government Hospital. The patients were on maintenance treatment including inhaled corticosteroids and bronchodilators according to the guideline treatment of asthma.
Result: In our present study, a total of 65 patients were included out of which 36(55.3%) were males. In our study, most of the patients were 51-70 years i.e., 36 out of 65(55.4%), followed by 31-50. The mean hsCRP in case group patients are 3.620.84 and in control group patients 0.830.15. Pulmonary lung function test using Spirometer was done in all the patients (case & control). The FEV1 values are compared against hsCRP values. Statistical significance is assessed using Spearmann’s correlation. Case group patients showing highly significant negative correlation of hsCRP with FEV1.
Conclusions: The results of this study indicate increased serum hsCRP concentration in asthma compared to controls. Increased serum hs-CRP correlates positively with severity of asthma and thus can be considered as a tool in predicting asthma status.

Keywords: Asthma, High sensitive Creactive protein, Forced expiratory volume.

How to cite : Krishna T U, Rao V V, Ahmed S U, Vishwanath B , A high-sensitivity C-reactive protein in assessing severity of asthma: A case control study. IP Indian J Immunol Respir Med 2021;6(2):86-89

Copyright © 2021 by author(s) and IP Indian J Immunol Respir Med. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (creativecommons.org)

Article History

Received : 13-03-2021

Accepted : 20-05-2021

Available online : 07-06-2021

View Article

PDF File   Full Text Article


PDF File   XML File   ePub File

Digital Object Identifier (DOI)

Article DOI


Article Metrics

Article Access statistics

Viewed: 423

PDF Downloaded: 159

Wiki in hindi